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Home OUR HEALTH  Health Mastery Q&A: What Causes Low HDL- the ‘good cholesterol’?
Thursday, February 10, 2011

Health Mastery Q&A: What Causes Low HDL- the ‘good cholesterol’?

by Dr. Dave Montgomery

Q: I’m really concerned about my husband who is overweight, has diabetes and now the doctor says his HDL cholesterol is low. What is HDL all about? Is there anything he can do?

A: Thanks for asking this important question. Let’s bring everybody up to speed on HDL cholesterol.

HDL, the so-called ‘good cholesterol’, is an acronym for high-density lipoprotein. The reason that we call it GOOD is because HDL actually acts by removing cholesterol from artery walls (and other places) where they form and build plaque.

Normal HDL > 40 mg/dL in men

> 50 mg /dL in women

Studies have shown the higher your HDL the lower is the incidence of coronary disease (plaque build up in heart arteries) and heart attacks (death of heart muscle due to artery blockages). Conversely, the lower the HDL the higher is the risk for cardiovascular disease.

There are a number of causes of low HDL (go to http://davemontgomerymd.com/ to read the quick tutorial on cholesterol), including inherited genetic abnormalities, obesity and insulin resistance, diabetes, high triglycerides, anabolic steroids and certain medications. Your husband likely has acquired a low HDL from type 2 diabetes and being overweight. There is a tight link between blood sugar, body weight and HDL cholesterol.

So, here are the things that we know increase HDL:

1. Daily aerobic exercise (at least 30 minutes a day)

2. Weight loss and tight control of diabetes (proper diet and taking medications on time as prescribed)

3. Nuts: walnuts, almonds, pistachios, etc.

4. Smoking cessation, where applicable

If these other measures don’t improve his HDL, medications may be necessary.

5. Niacin—prescription strength (often as high as 2000 mg daily) is one of the primary medications used to treat isolated low HDL.

6. Fibrates—another class of medicines that can increase HDL in some patients.

Ask your doctor about all of these and which are most suitable for your husband. Only your doctor can prescribe prescription strength niacin and fibrates.

The role of diet, exercise and medications, where applicable, cannot be over-emphasized. If there's room to work on any of these, then there’s hope to achieve a higher HDL.

Here's to Mastering Your Health

Dave Montgomery, MD, PhD is a Cardiologist at Northwestern University and a sought after Speaker and Health Coach. http://davemontgomerymd.com http://twitter.com/dmontgomerymd

 
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